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Catheter insertion, exchange or removal. Bladder drainage or urine collection.

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Gdańsk, Gdynia, Sopot

Vitamin C IV drip (IVC)

Intravenous infusions of vitamin C

Vitamin C (L-ascorbic acid, its salt – e.g. sodium ascorbate or an ester) is an antioxidant (inhibits the action of free radicals – reducing agent), helps in the fight against infections (many new publications contradict this property), increases iron absorption for Red blood cells (RBCs) production Vitamin C stimulates wound healing and regeneration of blood vessels its deficiency causes scurvy because ascorbic acid is responsible for the synthesis of collagen (the main protein of connective tissue). At the molecular level, ascorbic acid acts as an electron donor for enzymes involved in the hydroxylation of proline and lysine residues during collagen “maturation”. Ascorbic acid is a glucose derivative from which it can be produced by the cells of many animals (e.g. dogs) and plants. The human body does not have the ability to independently synthesize ascorbic acid, which it must receive from food. Laboratory studies on cell lines and animals have shown that high levels of vitamin C can inhibit the growth of various types of cancer. Vitamin C has been documented to selectively kill rectal cancer cells. Vitamin C causes the oxidation of glutathione (GSH) and the formation of reactive oxygen species (ROS), which cause DNA damage and cell apoptosis (death). Colon cancer cells produce large amounts of the enzyme GLUT1 – responsible for the transport of glucose inside the cells. The same protein (GLUT1) can transport the oxidized form of ascorbate – as a result of competition, the efficiency of glucose transport by the cell decreases. Additionally, reactive oxygen species can inactivate GLUT1 – inhibition of glucose transport. At the same time, it has been shown that some forms of vitamin C may weaken or increase the effectiveness of chemotherapeutic drugs. Achieving a high concentration of vitamin C in the body is possible by administering it directly into the bloodstream – using an IV drip. Clinical studies have shown that a high concentration of vitamin C after intravenous administration causes few side effects, and the maximum safe dose for a patient without contraindications is 1.5 g / kg. Patients with glucose-6-phosphate dehydrogenase deficiency, kidney diseases and suffering from haemochromatosis should avoid high doses of vitamin C. Intravenous ascorbate remains in the bloodstream for 4 hours, and its concentration is higher than after oral administration. The effectiveness of vitamin C therapy in cancer patients has been studied for about 45 years, but so far vitamin C has not been approved as a treatment for any disease other than scurvy. Dogs’ cells produce vitamin C, but dogs still get cancer. Sources and Links:

High-Dose Vitamin C

NIH Revisiting vitamin C and cancer Vitamin C could target some common cansers

Glucose deprivation contributes to the development of KRAS pathway mutations in tumor Cells

Effect of high-dose intravenous vitamin C on inflammation in cancer patients

FAO

Vitamin C protocol Riordan clinic

High-dose vitamin C linked to kidney stones in men

Witamina C jako oręż w walce z rakiem

Wlew dożylny z askorbinianu sodu

Naukowcy: witamina C podana dożylnie pomaga niszczyć raka

Frequently Asked Questions

What to pay special attention to when administering IVC?

  • Ascorbate interfere strip glucometers – important for diabetics.
  • Intravenous administration of vitamin C after a meal helps to reduce fluctuations in blood glucose levels.
  • High dose Vitamin C is best administered through the vascular port because ascorbate can cause inflammation of the peripheral veins.
  • Ascorbate may have chelating properties, therefore it can reduce the availability of calcium and magnesium ions.
  • High doses of vitamin C is considered to increase the risk of kidney stones.

What solution are used for IVC?

Vitamin C (ascorbic acid) is most often diluted in saline (0.9% NaCl). Sodium ascorbate can be diluted in water, not in saline – this allows to slightly reduce the amount of sodium cations administered to the patient (100 ml of saline contains 0.9 g of NaCl). Both ascorbic acid and sodium ascorbate in aqueous solution are in a dissociated form, i.e. in the form of ascorbate anion and hydrogen or sodium cation, respectively.

How many IVCs do you need to treat  cancer?

Vitamin C is not an anti-cancer drug and should not be an alternative to conventional therapies, but can be considered as adjunctive therapy. Vitamin C in combination therapy may reduce cytotoxicity, vomiting, nausea and improve the well-being of patients undergoing chemotherapy or radiotherapy, and may additionally strengthen their immune system. The results of studies carried out on cell lines or animal models indicate that the use of vitamin C may enhance or eliminate the anti-cancer effect of classic chemotherapeutic agents. There are no clinical trials that would confirm the effectiveness of vitamin C in oncotherapy. The fact that ascorbic acid or its derivatives exhibit antitumor activity in a cell or animal model does not mean that vitamin C is effective in humans.

Vitamin C decay when exposed to sun light?

Vitamin C is  photosensitive and it should be stored in the dark. However there is no need to use dark tubing and cover the drip during the infusion.

At what temperature should vitamin C be stored?

Vitamin C is stable at room temperature. Each drug should be stored in a manner consistent with the manufacturer’s instructions. Lowering the temperature may on one hand extend the shelf life of the product, but it may as well cause irreversible precipitation of the dissolved substance.

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The procedure is preceded by an interview and examination. We maintain outpatient standards .

IV drip:

Drip volume Price
To 250 ml 100 zl
To 500 ml 150 zł
To 1000 ml 200 zł
Type of drip Price
Antipyretic drip 200 zl
Pain drip 200 zł

Sodium ascorbate or ascorbic acid?

Sodium ascorbate is the sodium salt of ascorbic acid, which is used in the food industry as a preservative (E301).

In the body, this compound releases the sodium cation. In the case of intravenous administration of high doses of vitamin C, the use of sodium ascorbate may lead to hypernatraemia (excess sodium) and pose a threat to the health and life of the patient. At the same time, sodium ascorbate is a less acidic form of vitamin C than ascorbic acid, so it is less irritating to blood vessels and allows the use of higher doses and is easier to take orally. High doses of vitamin C are best administered through a central line or a vascular port, which avoids potential complications in the form of peripheral phlebitis.

Watcch video blog about sodium ascorbate infusions from https: //wlewy-dożylne.pl/. The film report does not take into account all the elements influencing the correct administration of the IV drip, but thanks to it you can gain a general idea of peripheral vein catheterization, preparation of infusion solutions, connection of a IV transfusion apparatus with venflon.